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Interstitial LDR
(low dose rate) brachytherapy of the prostate represents a
prostate cancer treatment with significantly reduced side effects
and less surgical risk. LDR brachytherapy is the implantation
of small, weak radio-active radiation sources (so-called seeds)
directly into the cancerous tissue. As these seeds are only about
0.8 mm in diameter and 4.5 mm in length, the implantation is
performed by injection through needles.
The seeds develop
their effect directly in the cancerous tissue, only a small dose
burden is exposed to adjacent organs. In long term studies the
healing rate was found to be comparable to the surgical removal of
the prostate. Currently more than 100,000 cases of prostate cancer
are treated per year worldwide by the implantation of seeds.
The
LDR brachytherapy treatment planning software PSID
(Permanent Seed Implant Dosimetry) for ultrasound guided radiation
therapy of prostate cancer developed by sonoTECH since 1999 is used
for treatment planning at numerous sites in Europe and beyond. The
use of advanced 3D visualization techniques allows an overview of
the planning results at unsurpassed speed and flexibility.
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| The planning is based
on sequence of ultrasound images which are loaded into the program
either by the integrated real time frame grabber, through a network
(DICOM TCP/IP) or from file. After contouring the organs with the
mouse, the program calculates the optimum seed distribution
depending on the desired dose levels in a few seconds. Alternatively
a partially edited seed distribution may be completed automatically
or the complete seed distribution may be placed manually. Isodoses
are updated immediately.
PSID
will automatically calculate the dose volume histogram, the
differential dose distribution, the natural dose volume histogram,
the needle loading plan and other parameters required to evaluate
the quality of the dose distribution. |
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| Based on the organ
contours PSID will calculate 3D views from any desired
viewing angle. The organ structures may be rotated in any direction.
Select the organs to be displayed with a mouse click. Choose whether
the seeds and / or needles should also be displayed. Naturally,
selected isodose surfaces will be displayed in 3D as well, if
desired.
Slice
the 3D structures in any direction to see where the seeds are
located, for example. Choose the transparency / opacity of each
organs you look right through the surface and see what is behind.
The 3D color-coded surface dose feature allows easy detection of hot
spots at organ surfaces. |
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| The needle loading
plan is the essential for seed placement. The plan describes how
to load the needles with seeds, where to position the needles and
how deep the needles are to be inserted into the prostate. If it is
desired to place the seeds at intermediate positions this will also
be displayed.
Manual
and Auto placement support single seeds as well as strands.
Ease of
operation and quick response times in combination with reliable seed
auto placement and seed finding features allow performing the
complete planning job in an unsurpassed short time period.
Please
contact us if you would like to receive more information on our
products. We will be happy to arrange a presentation, even at your
site. |
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Summary of PSID Version 4.5
Features:
- Image acquisition with frame grabber, files, DICOM
network, etc.
- Up
to 20 different image formats supported: DICOM, BMP, JPEG, TIFF,
GIF, PNG, etc.
- DICOM 3.0 TCP/IP network interface
- Co-registration (i.e. planning based on images from
different imaging modalities) of two image sequences with up
to 127 images per sequence.
- Algorithms and data for all common seed / strand types
are included or can easily be added by the build-in seed editor.
- Complies to the current AAPM TG-43 recommendations
(Supplement to the 2004 update of the AAPM Task Group No. 43
Report) dated May 2007. Accurate point and line source modeling of
the seed anisotropy is implemented.
- Easy
manual contouring of anatomical structures with the mouse
- Interpolation of missing contours on intermediate
slices
- Simple positioning of single seeds or Strands with a
mouse click on the template grid or on a finer grid
- Automatic placement results of seeds and strands are
unsurpassed by manual editing
- Interactive Online Planning during implantation based
on transversal and longitudinal real live ultrasound images (25
frames per second) even on Laptops - the exact needle and seed
positions can be used for online correction of the further
treatment
- A
manually edited incomplete partial placement of seeds and strands
can be completed automatically by the incremental automatic
placement feature.
- Real-time calculation of isodoses
during seed / strand positioning.
- Simultaneous application of
seeds with different activities in one study
- Immediate calculation of
local dose at cursor position
- Standard template geometries
and customer templates are selectable
- Visualization of calculation
results in 2D and 3D
- 3D isodoses and seed display, 3D organ surface depiction based
on the manually drawn contour
- User definable,
comprehensive report in color, consisting of more than 50 pages in
letter format including: Seed data, patient data, needle loading
plan, isodoses, doses volume histograms, histogram parameters,
etc. The report can be previewed before printing.
- Image Fusion between
Ultrasound-, MR and CT images for easier contouring during post
planning
- Automatic seed detecting algorithm for post planning based on
CT-images dramatically reduces the time required to create post
plans
- 2D isodoses and seed display in sagittal and coronal direction
- The Maximum Intensity Seed Navigator is a three dimensional
DRR (Digitally Reconstructed Radigraph) that can be also used for
editing the seeds.
- Seed setting and dragging in 2D even on oblique planes as well
as in the DRR. The DRR can be rotated in real time.
- Simple scaling of template
size and position
- User configurable depiction
of line thickness and color of contours, isodose lines,
seeds, etc.
- Multilingual operator
interface in English and German (Other languages on request).
- Needle loading display and
edit feature for the selected needle
- Image Fusion between image
sequences at any angle
- Conformal Index
COIN
- The amount of calculation points used for the determination of
the histograms is user definable independently for screen and
report. These calculation points are distributed on a
three-dimensional hexagonal grid to achieve a homogeneous filling
of the structure.
- Cumulated, differential and Natural Dose Volume Histogram
(NDVH) Natural Prescription Dose (NPD) and Natural Dose Ratio
(NDR) online and in the report.
- Online Vxx (Dose of Vol % of target volume), Dxx (Volume with
Dose > xx in Vol %) and Dcc (Volume Dose in cm³) Histogram
parameters updated online on the screen and printed in the report.
- CIVCO™ EXII™ stepper position encoder support for
automated acquisition of image sequences and automated tracking of
transversal and longitudinal plane in online planning mode..
- Multithreading (parallel processing) support: Increasing
the execution speed on computers with Quad Core™ processors by a
factor of four.
- Licensing with local dongle or with remote dongle (floating
license over a network) allows installation on several
computers.
- Intuitive operator guidance
- Build-in context sensitive
online help, i.e. for any object of the software the related
chapter of the help manual appears after pressing function key
[F1].
- Developed for Windows™ XP,
Windows™ Vista™ and Windows™ 7 in Administrator and Standard Mode.
and much, much
more... |
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Laptop Configuration
Example
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Intel® Core™2 Duo Prozessor T8100 (2.1 GHz, 3MB
L2-Cache, 800 MHz FSB)
- 4096 MB 667 MHz
Dual-Channel DDR2 SDRAM
- 320GB (7.200rpm)
Serial ATA Hard Drive
- Fixed Internal 8X
DVD+/-RW Slot Load Drive
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nVidia®
GeForce™ 8600M GS (128 Bit) 256 MB
- WXGA+-Display (1440 x
900) non glare
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Real Time Video Frame Grabber (PAL 50 Hz: 768 x 576
pixel / NTSC 60 Hz: 640 x 480 pixel )
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Microsoft™ Windows™ XP Professional
Operating System (Service Pack 3) or
Vista®
Business SP1 |
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